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CATEGORIES:Colloquium/Seminar
DESCRIPTION:Kate Bubar\, Biofrontiers Institute\, University of Colorado Bo
 ulder\n\nEstimating the overlap between malaria parasite sequence reads\n\n
 Over half a million people die from malaria every year. The disease pathoge
 nesis and subsequent fatality can be linked to PfEMP1\, a protein encoded b
 y var genes. Each parasite genome has sixty highly variable var genes. Chan
 ging the var gene that is expressed enables the infected red blood cells to
  avoid the immune system\, and the malaria infection persists. By quantifyi
 ng the number and frequency of identical var genes between malaria parasite
 s\, we hope to better understand the ways in which they evade the immune sy
 stem. I will first explain common measurements of beta diversity\, the dive
 rsity of species from one environment to another\, and why using these meas
 urements is a naive approach to this problem. I will then present our novel
  approach for estimating gene overlap from short read data and ideas for fu
 ture work.
DTEND:20191022T190000Z
DTSTAMP:20260508T151651Z
DTSTART:20191022T180000Z
GEO:40.006791;-105.262818
LOCATION:Engineering Center\, ECCR 257
SEQUENCE:0
SUMMARY:Math Bio Seminar - Kate Bubar
UID:tag:localist.com\,2008:EventInstance_31678796891118
URL:https://calendar.colorado.edu/event/math_bio_seminar_-_kate_bubar
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