Organic Seminar: Scott Miller, Yale University

Selective Catalytic Reactions in Complex Molecular Scaffolds

This lecture will describe recent developments in our efforts to develop catalysts for asymmetric reactions, in particular for the preparation of densely functionalized, stereochemically complex structures.  Over time, our foci have been on enantioselectivity, site-selectivity and chemoselectivity.  In much of our current work, we are studying issues of enantioselectivity as a prelude to extrapolation of catalysis concepts to more complex molecular settings where multiple issues are presented in a singular substrate.  Moreover, we continuously examine an interplay between screening of catalyst libraries and more hypothesis-driven experiments that emerge from screening results.  Some of the mechanistic paradigms, and their associated ambiguities, will figure strongly in the lecture.  The catalysts themselves most often emerge from amino acids and peptides, as illustrated in the accompanying graphic.

Student hosted: Wyatt Powell, Walczak lab

Scheduling contact: Kayla Jones

Tuesday, January 28, 2020 at 4:00pm

Cristol Chemistry and Biochemistry, CHEM 142
1606 Central Campus Mall, Boulder, CO 80309

Event Type

Lecture/Presentation, Colloquium/Seminar

Interests

Science & Technology, Research & Innovation, Outreach & Engagement

Audience

Students, Faculty, General Public, Postdoc

College, School & Unit

Arts & Sciences

Group
Chemistry
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