Organic Seminar: Scott Miller, Yale University
Selective Catalytic Reactions in Complex Molecular Scaffolds
This lecture will describe recent developments in our efforts to develop catalysts for asymmetric reactions, in particular for the preparation of densely functionalized, stereochemically complex structures. Over time, our foci have been on enantioselectivity, site-selectivity and chemoselectivity. In much of our current work, we are studying issues of enantioselectivity as a prelude to extrapolation of catalysis concepts to more complex molecular settings where multiple issues are presented in a singular substrate. Moreover, we continuously examine an interplay between screening of catalyst libraries and more hypothesis-driven experiments that emerge from screening results. Some of the mechanistic paradigms, and their associated ambiguities, will figure strongly in the lecture. The catalysts themselves most often emerge from amino acids and peptides, as illustrated in the accompanying graphic.
Student hosted: Wyatt Powell, Walczak lab
Scheduling contact: Kayla Jones
Tuesday, January 28, 2020 at 4:00pm
Cristol Chemistry and Biochemistry, CHEM 142
1606 Central Campus Mall, Boulder, CO 80309
- Event Type
- Interests
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Science & Technology, Research & Innovation, Outreach & Engagement
- Audience
- College, School & Unit
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